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Faculty

Faculty Directory

James E. Klaunig

Professor
Environmental Health Department

jklauni [at] indiana [dot] edu

(812) 856-2448
PH C040
Education
  • PD at CIIT Centers for Health Research, RTP, NC, 1991
  • PD at Medical University of Ohio, 1982
  • Ph.D. at University of Maryland, 1980
  • M.A. at Montclair State University, 1976
Background

2008-2012 - Member, Cancer Etiology Study Section, NCI/NIH

2005-2010 - Robert B. Forney Professor and Director of Toxicology, Indiana University

1991-2003 - Director, State Department of Toxicology, State Toxicologist, State of Indiana

2001 - IU Trustee Teaching Excellence Award

2002 - Kenneth P. DuBois Award, Midwest Toxicologist of the Year, Midwest Society of Toxicology

2003 - Sagamore of the Wabash, (Highest award for Service to the State from Indiana Governor)

2010 - George Scott Toxicologist Award

2009 - The H. Scott Memorial Award

Research:

Dr. Klaunig's research interests are dedicated to understanding the mechanisms of chemically induced toxicology and carcinogenesis with emphasis on human health and genetic and environmental factors affection human risk. His research has been supported by the NIH, USEPA, DOD, ACS, and non federal sources.

Curriculum Vitae

Publications

Roberts, R.A., Ganey, P.E., Ju, C., Kamendulis, L.M., Rusyn, I. Klaunig, J.E. (2007). Role of the Kupffer cell in mediating hepatic toxicity and carcinogenesis. Toxicological Sciences 96(1), 2-15.

Calabrese, E.J., Mattson, M. P., Klaunig, J.E., et al. (2007) Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Journal of Toxicology and Applied Pharmacology. 222, 122-128.

DePeyster, A., Rodriguez, Y., Shuto, R., Goldberg, B., Gonzales, F., Pu, X., Klaunig, J.E. (2008). Effect of oral methyl-t-butyl ether (MTBE) on the male mouse reproductive tract and oxidative stress in liver. Reproductive Toxicology , 26(3-4), 246-253.

Klaunig, J.E., Kamendulis, L.M., Hocevar, B.A. (2010). Oxidative stress and damage in carcinogenesis. Tox. Path. 38:96-109. (2009 Dec 17. Epub ahead of print)

Pu, X., Kamendulis, L.M., Klaunig, J.E. (2009). Acrylonitrile-induced oxidative stress and oxidative DNA damage in male Sprague-Dawley Rats. Toxicological Sciences, 111(1), 64-71.

Lee, L., Alloosh, M., Saxena, R., Van Alstine, W., Watkins, B., Klaunig, J.E., Sturek, M., Chalasani, N. (2009) Nutritional model of steatohepatitis and metabolic syndrome in the Ossabaw Island miniature swine. Hepatology 50(1), 56-67.